The Variety Of Red Yeast Rice Supplement Ingredients

A new study found that the ingredients of red yeast rice supplements vary in terms of amount. These ingredients are out in the market, and were introduced to lower cholesterol levels. Twelve of red yeast supplement products were subjected for the study, and the 4 of these had citrinin in detectable levels- potentially toxic and enough to damage the kidneys. This said ingredient is produced by a certain fungus.
In the year 2008 alone, Americans have already spent about $20 million dollars on red yeast rice supplements, hoping to give them hope to lower down the levels of bad cholesterol.
"Several studies have shown that specific formulations of red yeast rice reduce low-density lipoprotein [LDL or 'bad'] cholesterol significantly compared with placebo. This is likely related to the effects of monacolin K and the 13 other monacolins in the supplement, which also works to lower the production of cholesterol in the liver," according to the study lead by Dr. Ram Y. Gordon from Abington Memorial Hospital in Abington, Pa and Chestnut Hill Hospital.
Another ingredient available in red yeast rice supplements is the monacolin K. This ingredient is also a component of the drug Lovastatin (Mevacor)s, which is also responsible to cut the cholesterol level down. However, manufacturers normally do not reveal the levels of monacolin K or other monacolins in either red yeast rice supplements or on other medications to avoid being considered an unapproved drug.
In the study conducted for the red yeast rice, monacolin levels ranged from 0.31 mg. to 11.15 mg. per capsule. Meanwhile, the level of monacolin K in Lovastatin only ranges from 0.10 milligrams to 10 milligrams per capsule- which shows that the monacolin concentration in the red yeast rice is relatively higher. Researchers even added,
"Red yeast rice has been used for centuries for its medicinal properties and is an increasingly popular alternative lipid-lowering therapy that may benefit patients with a history of coronary disease who cannot take statins, subjects who refuse statins or who prefer a 'natural' approach to pharmacotherapy, or patients with a history of statin-associated myalgias [muscle pains]."
However, the researchers found a dramatic variability in red yeast rice products (in terms of monacolin levels), and also presence of citrinin, which raised their concern of having product standardization and labeling of the red yeast rice products. Until these concerns are addressed by the manufacturing companies, the researchers recommended that physicians should think several times before finally recommending red yeast rice to patients wanting to treat hyperlipidemia (otherwise known as high cholesterol), and prevent other forms of cardiovascular diseases.

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